TB-500 10mg

Description

TB-500 corresponds to the actin-binding domain of thymosin beta-4 (Tβ4), the most abundant intracellular G-actin-sequestering peptide in mammalian tissue. The fragment retains key biological activities attributed to the full-length protein, including promotion of cell migration and proliferation via upregulation of actin polymerization, modulation of angiogenic signaling through VEGF and angiopoietin-1 pathways, and anti-apoptotic activity in a range of cell types. Preclinical studies have applied TB-500 in wound healing models, cardiac injury paradigms, and neurological regeneration assays.

This lyophilized preparation is suitable for dissolution in sterile water or saline for use in cell culture migration assays, scratch wound healing experiments, and rodent tissue repair models. High purity ensures reliable dose-response characterization in receptor and downstream signaling studies. Vials should be stored at -20 degrees Celsius and used promptly following reconstitution to maintain peptide activity. For laboratory research use only. Not for human or veterinary use.